Soya isoflavones

Mu 1931, ndi nthawi yoyamba kudzipatula ndikuchotsa ku soya.
Mu 1962, ndi nthawi yoyamba kutsimikizira kuti ikufanana ndi mammalian estrogen.
Mu 1986, asayansi aku America adapeza ma isoflavones mu soya omwe amaletsa ma cell a khansa.
Mu 1990, National Cancer Institute ku United States inatsimikizira kuti soya isoflavones ndi zinthu zachilengedwe zabwino kwambiri.
Pakati ndi kumapeto kwa zaka za m'ma 1990, amagwiritsidwa ntchito kwambiri pamankhwala aumunthu, chisamaliro chaumoyo, chakudya ndi zina zotero.
Mu 1996, Us Food and Drug Administration (FDA) idavomereza soya isoflavones ngati chakudya chaumoyo.
Mu 1999, Us Food and Drug Administration (FDA) idavomereza soya isoflavones chakudya chogwira ntchito kuti chilowe mumsika waku US.
Kuyambira 1996, zakudya zopitilira 40 zokhala ndi soya isoflavones zavomerezedwa ku China.

Titha kupereka mitundu yosiyanasiyana ya soya isoflavones malinga ndi zomwe kasitomala amafuna.
1. Soy isoflavones 5% -90%
5% Soya isoflavones amagwiritsidwa ntchito kwambiri m'munda wa chakudya, Flavonoids ali ndi zochitika zodziwikiratu zamoyo mu nyama, zomwe zimatha kulimbikitsa kukula kwa nyama, kuchepetsa kuyika kwamafuta am'mimba, kukonza uchembere komanso kulimbitsa chitetezo chokwanira.
Lamulo la kukula kwa ziweto zamphongo ndi nkhuku

Zotsatira zinasonyeza kuti kukula kwa korona kunakula mofulumira, kulemera kwa tsiku ndi tsiku kumawonjezeka ndi 10%, kulemera kwa chifuwa ndi miyendo ya miyendo kunawonjezeka ndi 6.5% ndi 7.26% motsatira, ndipo kuchuluka kwa kugwiritsidwa ntchito kwa chakudya kunachepetsedwa kwambiri.Zomwe zili mu DNA pa gramu ya minofu ya pachifuwa zinatsika ndi 8.7% poyerekeza ndi gulu lolamulira, koma panalibe kusintha kwakukulu kwa DNA ya pectoralis, ndi RNA yonse yawonjezeka ndi 16.5%, mlingo wa seramu urea unatsika ndi 14.2%, kugwiritsa ntchito mapuloteni. kuchuluka kwake kunakwera kwambiri, koma sikunakhudze kwambiri nkhuku zachikazi.Zotsatira zinasonyeza kuti milingo ya testosterone, β - endorphin, hormone ya kukula, insulini-monga kukula factor-1, T3, T4 ndi insulini inali yabwino kwambiri.Zotsatira zofananazo zinapezedwa mu kuyesa kwa bakha a Gaoyou, ndi kulemera kwa tsiku ndi tsiku kunawonjezeka ndi 16.92%, kugwiritsa ntchito chakudya kumawonjezeka ndi 7.26%.Kuchuluka kwa mahomoni okula mu seramu kunakwera ndi 37.52% powonjezera 500mg/kg soya isoflavones pazakudya za nkhumba, ndipo kuchuluka kwa urea nitrogen ndi cholesterol ya metabolites kudachepa kwambiri.

Mmene kupanga ntchito atagona nkhuku
Zotsatira zake zidawonetsa kuti kuchuluka koyenera kwa daidzein (3-6mg / kg) kumatha kutalikitsa nthawi yoyikira, kuonjezera kuchuluka kwa kaikidwe, kulemera kwa dzira ndi kutembenuka kwa chakudya.Kuonjezera 6mg / kg daidzein pazakudya za zinziri zogona za miyezi 12 zitha kukulitsa kuchuluka kwa kugona ndi 10.3% (P0.01).Kuonjezera 3mg / kg daidzein pazakudya za Shaoxing atagona abakha kumatha kukulitsa kuchuluka kwa magonedwe ndi 13.13% ndikusintha kwa chakudya ndi 9.40%.Kafukufuku wa mamolekyulu a biology atsimikizira kuti soya isoflavones imatha kulimbikitsa kwambiri GH gene expression ndi GH zomwe zili mu nkhuku, kuti zilimbikitse kubereka.

Zotsatira za Daidzein pa nkhumba zapakati
Ngakhale kuti kagulu ka nkhumba kamene kamakhala kothandiza kwambiri kamene kamakhala ndi kadyetsedwe kamene kamabereka, kamasowa njira zoyendetsera kukula kwa ana a nkhumba kudzera mwa nkhumba.Kupyolera mu ndondomeko ya neuroendocrine ya amayi, kusintha katulutsidwe ka zakudya, kulimbikitsa kukula kwa mwana wosabadwa komanso kupititsa patsogolo ubwino ndi kuchuluka kwa lactation ndizofunikira kwambiri kuti nkhumba ikhale yogwira ntchito.Zotsatirazo zinasonyeza kuti pambuyo pofesa zowawa zapakati kudyetsedwa ndi daidzein, mlingo wa insulini wa plasma unachepa ndipo mlingo wa IGF unakula.Kuyamwitsa kwa nkhumba pa tsiku la 10 ndi 20 linali 10.57% ndi 14.67% kuposa la gulu lolamulira, motero.Poyerekeza ndi gulu lolamulira, zomwe zili mu GH, IGF, TSH ndi PRL mu colostrum zinawonjezeka kwambiri, koma zomwe zili mu dzira loyera zinalibe kusintha kwakukulu.Kuphatikiza apo, kuchuluka kwa ma antibody mu colostrum kumawonjezeka ndipo kupulumuka kwa ana a nkhumba kumawonjezeka.
Soy isoflavones amatha kuchitapo kanthu mwachindunji pa ma lymphocyte ndikulimbikitsa kusintha kwa ma lymphocyte komwe kumapangidwa ndi PHA ndi 210%.Ma isoflavones a soya amatha kupititsa patsogolo chitetezo chokwanira komanso chitetezo chamthupi cha ziwalo za mabere.Anti classical swine fever antibody m'magazi a nkhumba zapakati mu gulu loyesera idakwera ndi 41%, ndipo mu colostrum idakwera ndi 44%

Zotsatira pa zoweta
Zotsatira zake zidawonetsa kuti soya isoflavones zitha kukhudza mwachindunji zochita za michere yayikulu yam'mimba ya tinthu tating'onoting'ono ta rumen ndikuwongolera kugaya kwawo,.Mu vivo, chithandizo cha soya isoflavones chinakulitsa kwambiri mlingo wa testosterone wa njati zamphongo ndi nkhosa, kuchulukitsa mapuloteni a rumen microbial ndi kuchuluka kwa mafuta osasunthika a asidi, ndikupititsa patsogolo kukula ndi kupanga mphamvu za zinyama.

Chikoka pa achinyamata nyama
Kale, kuswana kwa ana ang’onoang’ono kunkayamba akangobadwa, koma m’lingaliro lake, kunali kuchedwa kwambiri.Mayesero anasonyeza kuti mankhwala a mimba yofesa ndi soya isoflavones osati kuchuluka mkaka wa m`mawere, komanso kuchuluka akulimbana akuchikazi mu mkaka.Kukula kwa ana a nkhumba a colostrum kunawonjezeka ndi 11%, ndipo chiwerengero cha ana a nkhumba a masiku 20 chinawonjezeka ndi 7.25% (96.2% vs 89.7%);phindu latsiku ndi tsiku, testosterone ndi magazi a calcium okhutira a nkhumba zamphongo zoletsedwa zawonjezeka ndi 59.15%, 18.41% ndi 17.92%, motero, pamene a nkhumba zaakazi amasiya kuyamwa anawonjezeka ndi 5 mg / kg soya isoflavones 39%, - 6. 86%, 6 47 %.Izi zimatsegula njira yatsopano yoweta ana a nkhumba.

Aglycon Soy Isoflavones
Soya isoflavones mu soya ndi soya chakudya makamaka amakhala mu mawonekedwe a glycoside, amene samwedwa mosavuta ndi thupi la munthu.Poyerekeza ndi glucoside isoflavones, soya isoflavone yaulere imakhala ndi zochita zambiri chifukwa imatha kuyamwa mwachindunji ndi thupi la munthu.Pakadali pano, ma isoflavone 9 ndi ma glucoside atatu ofanana (ie ma isoflavone aulere, omwe amadziwikanso kuti glucosides) asiyanitsidwa ndi soya.

Ma Isoflavones ndi mtundu wa metabolites wachiwiri wopangidwa mukukula kwa soya, makamaka mu majeremusi ndi chakudya cha soya chambewu za soya.Ma Isoflavones akuphatikizapo daidzein, soya glycoside, genistein, genistein, daidzein, ndi soya.Ma isoflavone achilengedwe nthawi zambiri amakhala mu mawonekedwe a β - glucoside, omwe amatha kupangidwa ndi hydrolyzed kukhala isoflavones yaulere pansi pa zochita za isoflavones glucosidase zosiyanasiyana.7, Daidzein (daidzein, yemwe amadziwikanso kuti daidzein) ndi chimodzi mwazinthu zazikulu zomwe zimagwira ntchito mu soya isoflavones.Zimadziwika kuti ili ndi ntchito zambiri zakuthupi pathupi la munthu.Mayamwidwe a Daidzein m'thupi la munthu makamaka amachokera ku njira ziwiri: liposoluble glycosides amatha kuyamwa mwachindunji kuchokera m'matumbo aang'ono;glycosides mu mawonekedwe a glycosides sangadutse khoma la matumbo aang'ono, koma sangathe kutengeka kudzera m'matumbo aang'ono khoma Imasungunuka ndi glucosidase m'matumbo kuti apange glycoside ndipo imatengedwa ndi matumbo.Zotsatira zakuyesa kwa anthu zidawonetsa kuti soya isoflavone idalowetsedwa makamaka m'matumbo, ndipo kuchuluka kwa mayamwidwe kunali 10-40%.Soy isoflavones adamwedwa ndi microvilli, ndipo gawo laling'ono limatulutsidwa m'matumbo am'mimba ndi bile, ndipo adatenga nawo gawo pakuyenda kwa chiwindi ndi bile.Ambiri aiwo adawonongeka ndikusinthidwa ndi tizilombo tating'onoting'ono m'matumbo ndi heterocyclic lysis, ndipo zinthuzo zimatha kulowa m'magazi.Ma isoflavones opangidwa ndi metabolites amatulutsidwa kudzera mumkodzo.
Soya isoflavones makamaka amakhala mu mawonekedwe a glucosides, pamene mayamwidwe ndi kagayidwe soya isoflavones mu thupi la munthu ikuchitika mu mawonekedwe a soya isoflavones ufulu.Chifukwa chake, ma isoflavones aulere amakhalanso ndi dzina la "isoflavones yogwira ntchito".
Madzi sungunuka Soya isoflavones 10%